平野丈夫 名誉教授 (1997.3-2021.3在職)

A 著書

  1. Takahashi, K. and Hirano, T.(1983) "Development of calcium channels in the membrane of the cleavage-arrested embryo of ascidians." In: Physiology of Excitable Cells. (eds) Grinnell, A.D. and Moody, W.J.Jr. Alan R. Liss, New York, pp279-289.
  2. Kidokoro, Y., Ohmori, H. and Hirano, T.(1985) "Acetylcholine-activated currents in the rat adrenal chromaffin cell in culture." In: neurosecretion and the Biology of Neuropeptides. (eds) Kobayashi, H., Bern, H.A.and Urano, A., Japanese Science Society Press, Tokyo and Springer-Verlag, Belin. pp96-101.
  3. 平野丈夫(1992)「培養下における同定小脳ニューロン間のシナプス伝達の増強と抑圧」脳と学習のメカニズム(松本元編著), pp173-181, 丸善(東京)
  4. 平野丈夫(1993)「小脳培養系におけるシナプスと可塑性」ブレインサイエンス最前線'94, 講談社サイエンテイフィック, pp98-109.
  5. Hirano, T.(1996) "Involvement of the ionotropic glutamate receptor d2 subunit in cerebellar long-term depression, motor control and motor learning." In: Gene targeting and new developments in neurobiology. (eds) Nakanishi, S., Silva, A. J., Aizawa, S. & Katsuki, M., Japan Scientific Societies Press, Tokyo, pp17-24.
  6. Hirano, T.(1996) "Molecular basis of the cerebellar long-term depression" In: Brain Processes and Memory (eds) Ishikawa, K., McGaugh, J. L. & Sakata, H., Elsevier, Amsterdam, pp269-277.
  7. 平野丈夫(1997)「可塑性の分子メカニズム」脳と計算論(外山敬介・杉江昇編集), 朝倉書店, pp73-89.
  8. 平野丈夫(1999)「脳・神経」分子生物学(柳田充弘・西田栄介・野田亮編集), 東京化学同人, pp256-270.
  9. 平野丈夫(2000)「パッチクランプ法」脳科学大事典(甘利俊一・外山敬介編集), 朝倉書店, pp71-74.
  10. 平野丈夫(2000)「分子生物学的手法」脳科学大事典(甘利俊一・外山敬介編集), 朝倉書店, pp96-99.
  11. 平野丈夫(2001)「脳と心の正体:神経生物学者の視点から」東京化学同人, pp1-141.
  12. Kawaguchi, S. and Hirano, T.(2008) "Regulatory mechanism of plasticity at GABAA receptor-mediated synapse." In: Amino Acid Receptor Research., Nova Science Publishers, Inc., Ed. B. J. Paley and T. E. Warfield, pp138-158.
  13. Tsuruno, S. and Hirano, T.(2008) "Synaptic plasticity and motor learning in the cerebellum." In Synaptic Plasticity: New Research., Ed. T. F. Kaiser and F. J. Peters, Nova Science Publishers, Inc., pp143-161.
  14. Hirano, T.(2008) "Sensory motor learning / memory and cerebellum." In Encyclopedia of Neuroscience, Springer, 3654-3657.
  15. Kawaguchi, S. and Hirano, T.(2010) "Molecular mechanism of long-term plasticity at cerebellar inhibitory synapses" In Inhibitory Synaptic Plasticity, Springer, (eds) Woodin, M. A. & Maffei, A., ISBN 978-1-4419-6977-4.
  16. Hirano, T.(2013) "GABA and synaptic transmission in the cerebellum" In Handbook of the Cerebellum and Cerebellar Disorders, Springer, (eds) Manto, M., Schmahmann, J. D., Rossi, F., Gruol, D. L. and Koibuchi, N. ISBN: 978-94-007-1332-1, pp881-893.
  17. Hirano, T.(2016) "GABA pathways and receptors." In Essentials of cerebellum and cerebellar disorders, Springer, (eds) Gruol, D. L., Koibuchi, N., Manto, M., Molonari, M., Schmahmann, J. D. and Shen, Y. ISBN: 978-3-319-24549-2, pp225-229.
  18. 平野丈夫(2019)「何のための脳? AI時代の行動選択と神経科学」京都大学学術出版会, pp1-145.
  19. Hirano, T. and Inoshita, T.(2021) "Contribution of norepinephrine to cerebellar long-term depression and motor learning" In Cerebellum as a CNS hub, Springer, (eds) Mizusawa, H., Kakei, S., pp337-348.
  20. 平野丈夫(2021)「自己とは何なのか? 意識・自我・心についての神経科学的考察」幻冬舎メディアコンサルティング, pp1-152.

B 原著論文

  1. Hirano, T. and Takahashi, K.(1981) "Physiological and morphological properties of large neurones in the freshwater snail, Indoplanorbis exustus (Deshayes)" J. Faculty of Science, University of Tokyo, Section 4, 15: 9-23.
  2. Hirano, T. and Takahashi, K.(1983) "Ionic mechanisms of action potentials in identified neurons of the freshwater snail, Indoplanorbis exustus (Deshayes)" Comp. Biochem. Physiol., 74A: 579-585.
  3. Hirano, T., Takahashi, K. and Yamashita, N.(1984) "Determination of excitability types in blastomeres of the cleavage-arrested but differentiated embryos of an ascidian" J. Physiol. (London), 347: 301-325.
  4. Hirano,T. and Takahashi, K.(1984) "Comparison of properties of calcium channels between the differentiated 1-cell embryo and the egg cell of ascidians" J. Physiol. (London), 347: 327-344.
  5. Hirano, T. and Ohmori, H.(1986) "Voltage-gated and synaptic currents in rat Purkinje cells in dissociated cell cultures" Proc. Natl. Acad. Sci. USA, 83: 1945-1949.
  6. Hirano, T., Kubo, Y. and Wu, M.M.(1986) "Cerebellar granule cells in culture: monosynaptic connections with Purkinje cells and ionic currents" Proc. Natl, Acad. Sci. USA, 83: 4957-4961.
  7. Hirano, T., Kidokoro, Y. and Ohmori, H.(1987) "Acetylcholine dose-response relation and the effect of cesium ions in the rat adrenal chromaffin cell under voltage clamp" Pflugers Arch (Eur. J. Physiol.), 408: 401-407.
  8. Hirano, T. and Takahashi, K.(1987) "Development of ionic channels and cell-surface antigens in the cleavage-arrested one-cell embryo of an ascidian" J. Physiol. (London), 386: 113-133.
  9. Hirano, T. and Hagiwara, S.(1988) "Synaptic transmission between rat cerebellar granule and Purkinje cells in dissociated cell culture: effects of excitatory-amino acid transmitter antagonists" Proc. Natl. Acad. Sci. USA, 85: 934-938.
  10. Hirano,T. and Hagiwara,S.(1989) "Kinetics and distribution of voltage-gated Ca, Na and K channels on the somata of rat cerebellar Purkinje cells" Pflugers Arch (Eur . J. Physiol.), 413: 463-469.
  11. Hirano, T.(1990) "Synaptic transmission between rat inferior olivary neurons and cerebellar Purkinje cells in culture" J. Neurophysiol., 63: 181-189.
  12. Hirano, T.(1990) "Depression and potentiation of the synaptic transmission between a granule cell and a Purkinje cell in rat cerebellar culture" Neurosci. Lett., 119: 141-144.
  13. Hirano, T.(1990) "Effects of postsynaptic depolarization in the induction of synaptic depression between a granule cell and a Purkinje cell in rat cerebellar culture" Neurosci. Lett., 119: 145-147.
  14. Hirano, T.(1991) "Differential pre- and postsynaptic mechanisms for synaptic potentiation and depression between a granule cell and a Purkinje cell in rat cerebellar culture" Synapse, 7: 321-323.
  15. Hirano, T. and Kasono, K.(1993) "Spatial distribution of excitatory and inhibitory synapses on a Purkinje cell in a rat cerebellar culture" J. Neurophysiol., 70: 1316-1325.
  16. Shigemoto, R., Abe, T., Nomura, S., Nakanishi, S. and Hirano, T.(1994) "Antibodies inactivating mGluR1 metabotropic glutamate receptor block long-term depression in cultured Purkinje cells" Neuron, 12: 1245-1255.
  17. Hirano, T., Kasono, K., Araki, K., Shinozuka, K. and Mishina, M.(1994) "Involvement of the glutamate receptor d2 subunit in the long-term depression of glutamate responsiveness in cultured rat Purkinje cells" Neurosci. Lett., 182: 172-176.
  18. Kasono, K. and Hirano, T.(1994) "Critical role of postsynaptic calcium in the cerebellar long-term depression" NeuroReport, 6: 17-20.
  19. Hirano, T., Kasono, K., Araki, K. and Mishina, M.(1995) "Suppression of LTD in cultured Purkinje cells deficient in the glutamate receptor d2 subunit" NeuroReport, 6: 524-526.
  20. Kasono, K. and Hirano, T.(1995) "Involvement of inositol trisphosphate in the cerebellar long-term depression" NeuroReport, 6: 569-572.
  21. Kashiwabuchi, N., Ikeda, K., Araki, K., Hirano, T., Shibuki, K., Takayama, C., Inoue, Y., Kutsuwada, T., Yagi, T., Kang, Y., Aizawa, S. and Mishina, M.(1995) "Disturbed motor coordination, Purkinje cell synapse formation and cerebellar long-term depression of mice defective in the d2 subunit of the glutamate receptor channel" Cell, 81: 245-252.
  22. Funabiki, K., Mishina,M. and Hirano,T.(1995) "Retarded vestibular compensation in the mutant mice deficient of d2 glutamate receptor subunit" NeuroReport, 7: 189-192.
  23. Kadotani, H., Hirano, T., Masugi, M., Nakamura, K., Nakao, K., Katsuki, M. and Nakanishi, S.(1996) "Motor discoordination results from combined gene disruption of the NMDA receptor NR2A and NR2C subunits, but not from single disruption of the NR2A or NR2C subunit" J. Neurosci., 16: 7859-7867.
  24. Kawasaki, H., Morooka,T., Shimohama, S., Kimura, J., Hirano,T., Gotoh, Y. and Nishida, E.(1997) "Activation and involvement of p38 mitogen-activated protein kinase in glutamate-induced apoptosis in rat cerebellar granule cells" J. Biol. Chem., 272: 18518-18521.
  25. Watanabe, D., Inokawa, H., Hashimoto, K., Suzuki, N., Kano, M., Shigemoto, R., Hirano, T., Toyama, K., Kaneko, S., Yokoi, M., Moriyoshi, K., Suzuki, M., Kobayashi, K., Nagatsu, T., Kreitman, R. J., Pastan, I. and Nakanishi, S.(1998) "Ablation of cerebellar Golgi cells disrupts synaptic integration involving GABA inhibition and NMDA receptor activation in motor coordination" Cell, 95: 17-28.
  26. Kawasaki, H., Fujii, H., Gotoh, Y., Morooka, T., Shimohama, S., Nishida, E. and Hirano, T.(1999) "Requirement for mitogen-activated protein kinase in cerebellar long-term depression" J. Biol. Chem., 274: 13498-13502.
  27. Murashima, M. and Hirano, T.(1999) "Entire course and distinct phases of day-lasting depression of mEPSC amplitudes in cultured Purkinje neurons" J. Neurosci., 19: 7326-7333.
  28. Yamakawa, Y. and Hirano, T.(1999) "Contribution of mGluR1 to the basal activity of a mouse cerebellar Purkinje neuron" Neurosci. Lett., 277: 103-106.
  29. Kawaguchi, S. and Hirano, T.(2000) "Suppression of inhibitory synaptic potentiation by presynaptic activity through postsynaptic GABAB receptors in a Purkinje neuron" Neuron, 27: 339-347.
  30. Imamura, Y., Inokawa, H., Ito, A., Kadotani, H., Toyama, K., Noda, S., Nakanishi, S. and Hirano, T.(2000) "Roles of GABAergic inhibition and NMDA receptor subunits in the spatio-temporal integration in the cerebellar cortex of mice" Neurosci. Res., 38: 289-301.
  31. Iwashita, M., Kanai, R., Funabiki, K., Matsuda, K. and Hirano, T.(2001) "Dynamic properties, interactions and adaptive modifications of vestibulo-ocular reflex and optokinetic response in mice" Neurosci. Res., 39: 299-311.
  32. Yamasaki, T., Kawaji, K., Ono, K., Bito, H., Hirano, T., Osumi, N. and Kengaku, M.(2001) "Pax6 regulates granule cell polarization during parallel fiber formation in the developing cerebellum" Development, 128, 3133-3144.
  33. Kawaguchi, S. and Hirano, T.(2002) "Signaling cascade regulating long-term potentiation of GABAA receptor responsiveness in cerebellar Purkinje neurons" J. Neurosci., 22, 3969-3976.
  34. Eiraku,M., Hirata,Y., Takeshima, H., Hirano, T. and Kengaku, M.(2002) "Delta/Notch-like epidermal growth factor (EGF)-related receptor, a novel EGF-like repeat–containing protein targeted to dendrites of developing and adult central nervous system neurons" J. Biol. Chem., 277, 25400-25407.
  35. Fujii, H. and Hirano, T.(2002)"Calcineurin regulates induction of late phase of cerebellar long-term depression in rat cultured Purkinje neurons" Eur. J. Neurosci., 16, 1777-1788.
  36. Minami, I., Kengaku, M., Sillevis Smitt, P., Shigemoto, R. and Hirano, T.(2003) "Long-term potentiation of mGluR1 activity by depolarization-induced Homer1a in cerebellar Purkinje neurons" Eur. J. Neurosci., 17, 1023-1032.
  37. Coesmans, M., Sillevis Smitt, P. A., Linden, D. J., Shigemoto, R., Hirano, T., Yamakawa, Y., Van Alphen, A. M., Luo, C., Van Der Geest, J. N., Kros, J., M., Gaillard, C. A., Frens, M. A. and De Zeeuw, C. I.(2003) "Mechanism underlying cerebellar motor deficits due to mGluR1-autoantibodies" Ann. Neurol., 53, 325-336.
  38. Kitano, J., Nishida, M., Itsukaichi, Y., Minami, I., Ogawa, M., Hirano, T., Mori, Y. and Nakanishi, S.(2003) "Direct interaction and functional coupling between metabotropic glutamate receptor subtype 1 and voltage-sensitive CaV2.1 Ca2+ channel" J. Biol. Chem., 278, 25101-25108.
  39. Murai, N., Tsuji, J., Ito, J., Mishina, M. and Hirano, T.(2004) "Vestibular compensation in glutamate receptor delta-2 subunit knockout mice: dynamic property of vestibule-ocular reflex" European Archives of Oto-Rhino-Laryngology, 261, 82-86.
  40. Kawaji, K., Umeshima, H., Eiraku, M., Hirano T. and Kengaku, M.(2004) "Dual phases of migration of cerebellar granule cells guided by axonal and dendritic leading processes" Mol. Cell. Neurosci., 25, 228-240.
  41. Yoshida, T., Katoh, A., Ohtsuki, G., Mishina, M. and Hirano, T.(2004) "Oscillating Purkinje neuron activity causing involuntary eye movement in a mutant mouse deficient in the glutamate receptor d2 subunit" J. Neurosci., 24, 2440-2448.
  42. Shima, Y., Kengaku, M., Hirano, T., Takeichi, M. and Uemura, T.(2004) "Regulation of dendritic maintenance and growth by a mammalian 7-pass transmembrane cadherin" Dev. Cell, 7, 205-216.
  43. Ohtsuki, G., Kawaguchi, S., Mishina, M. and Hirano, T.(2004) "Enhanced inhibitory synaptic transmission in the cerebellar molecular layer of the GluRδ2 knockout mouse" J. Neurosci., 24, 10900-10907.
  44. Katoh, A., Yoshida, T., Himeshima, Y., Mishina, M. and Hirano, T.(2005) "Defective control and adaptation of reflex eye movements in mutant mice deficient in either the glutamate receptor d2 subunit or Purkinje cells" Eur. J. Neurosci., 21, 1315-1326.
  45. Eiraku, M., Tohgo, A., Ono, K., Kaneko, M., Fujishima, K., Hirano, T. and Kengaku, M.(2005) "DNER acts as a neuron-specific Notch ligand during Bergmann glial development" Nature Neurosci., 8, 873-880.
  46. Tohgo, A., Eiraku, M., Miyazaki, T., Miura, E., Kawaguchi, S., Nishi, M., Watanabe, M., Hirano, T., Kengaku, M. and Takeshima, H.(2006) "Imapired cerebellar functions in mutant mice lacking DNER" Mol. Cell. Neurosci., 31, 326-333.
  47. Kawaguchi, S. and Hirano, T.(2006) "Integrin a3b1 suppresses long-term potentiation at inhibitory synapses on the cerebellar Purkinje neuron" Mol. Cell. Neurosci., 31, 416-426.
  48. Yawata, S., Tsuchida, H., Kengaku, M. and Hirano, T.(2006) "Membrane-proximal region of GluRd2 is critical for LTD and interaction with PICK1 in a cerebellar Purkinje neuron" J. Neurosci., 26, 3626-3633.
  49. Yoshida, T., Funabiki, K. and Hirano, T.(2007) "Increased occurrence of climbing fiber inputs to the cerebellar flocculus in a mutant mouse is correlated with the timing delay of optokinetic response" Eur. J. Neurosci., 25, 1467-1474.
  50. Tsuruno, S. and Hirano, T.(2007) "Persistent activation of protein kinase Cα is not necessary for expression of cerebellar long-term depression" Mol. Cell Neurosci., 35, 38-48.
  51. Fujishima, K., Kurisu, J., Hirano, T. and Kengaku, M.(2007) "Targeted disruption of Sept3, a binding partner of Sept5 and Sept7, unaffects neuronal development in the central nervous system" J. Neurochem., 102, 77-92.
  52. Mizuno, H., Hirano, T. and Tagawa, Y.(2007) "Evidence for activity-dependent cortical wiring: formation of interhemispheric connections in neonatal mouse visual cortex requires projection neuron activity" J. Neurosci., 27, 6760-6770.
  53. Kawaguchi, S. and Hirano, T.(2007) "Sustained GABARAP structural change underlies long-term potentiation at inhibitory synapses on a cerebellar Purkinje neuron" J. Neurosci., 27, 6788-6799.
  54. Shima, Y., Kawaguchi, S., Kosaka, K., Nakayama, M., Hoshino, M., Nabeshima, Y., Hirano, T. and Uemura, T.(2007) "Opposing roles in neurite growth control by two 7-pass transmembrane cadherins" Nat. Neurosci., 10, 963-969.
  55. Umeshima, H., Hirano, T. and Kengaku, M.(2007) "Microtuble-based nuclear movement occurs independently of centrosome positioning in migrating neurons" Proc. Natl. Acad. Sci. USA, 104, 16182-16187.
  56. Wada, N., Kishimoto, Y., Watanabe, D., Kano, M., Hirano, T., Funabiki, K. and Nakanishi, S.(2007) "Conditioned eyeblink learning is formed and stored without cerebellar granule cell transmission" Proc. Natl. Acad. Sci. USA, 104, 16690-16695.
  57. Sugiyama, Y., Kawaguchi, S. and Hirano, T.(2008) "mGluR1-mediated facilitation of long-term potentiation at inhibitory synapses on a cerebellar Purkinje neuron" Eur. J. Neurosci., 27, 884-896.
  58. Tsuruno, S., Kawaguchi, S. and Hirano, T.(2008) "Src-family protein tyrosine kinase negatively regulates cerebellar long-term depression" Neurosci. Res., 61, 329-332.
  59. Takeuchi, T., Ohtsuki, G. Yoshida, T., Fukaya, M., Wainai, T., Yamashita, M., Yamazaki, Y., Mori, H., Sakimura, K., Kawamoto, S., Watanabe, M., Hirano, T. and Mishina, M.(2008) "Enhancement of both long-term depression induction and optokinetic response adaptation in mice lacking delphilin" PLoS One, 3, e22 S 97, 1-11.
  60. Ohtsuki, G. and Hirano, T.(2008) "Bidirectional plasticity at developing climbing fiber – Purkinje neuron synapses" Eur. J. Neurosci., 28, 2393-2400.
  61. Kuroyanagi, T., Yokoyama, M. and Hirano, T.(2009) "Postsynaptic glutamate receptor d family contributes to presynaptic terminal differentiation and establishment of synaptic transmission" Proc. Natl. Acad. Sci. USA, 106, 4912-4916.
  62. Kitagawa, Y., Hirano, T. & Kawaguchi, S.(2009) "Prediction and validation of a mechanism to control the threshold for inhibitory synaptic plasticity" Mol. Systems. Biol., 5, 280, 1-16.
  63. Ageta-Ishihara, N., Takemoto-Kimura, S., Nonaka, M., Adachi-Morishima, A., Suzuki, K., Kamijo, S., Fujii, H., Mano, T., Blaeser, F., Chatila, T., Mizuno, H., Hirano, T., Tagawa, Y., Okuno, H. and Bito, H.(2009) "Control of cortical axon elongation by a GABA-driven Ca2+ calmodulin-dependent protein kinase cascade" J. Neurosci., 29, 13720-13729.
  64. Mizuno, H., Hirano, T. and Tagawa, Y.(2010) "Pre- and postsynaptic neuronal activity supports the axon development of callosal projection neurons during different postnatal periods in the mouse cerebral cortex" Eur. J. Neurosci., 31, 410-424.
  65. Kuroyanagi, T. & Hirano, T.(2010) "Flap loop of GluD2 binds to Cbln1 and induces presynaptic differentiation" Biochem. Biophys. Res. Commun., 398, 537-541.
  66. Muguruma, K., Nishiyama, A., Ono, Y., Miyawaki, H., Mizuhara, E., Hori, S., Kakizuka, A., Obata, K., Yanagawa, Y., Hirano, T. & Sasai, Y.(2010) "Ontogeny-recapitulating generation and tissue integration of ES cell-derived Purkinje cells" Nature Neurosci., 13, 1171-1180.
  67. Kurisu, J., Fukuda, T., Yokoyama, S., Hirano, T. & Kengaku, M.(2010) "Polarized targeting of DNER into dendritic plasma membrane in hippocampal neurons depends on endocytosis" Journal of Neurochemistry, 113, 1598-1610.
  68. Miyawaki, H. & Hirano, T.(2011) "Different correlations among physiological and morphological properties at single glutamatergic synapses in the rat hippocampus and the cerebellum" Synapse, 65, 412-423.
  69. Kawaguchi, S., Nagasaki, N. & Hirano, T.(2011) "Dynamic impact of temporal context of Ca2+ signals on inhibitory synaptic plasticity" Scientific Reports, 1, 143; 1-12.
  70. Ryu, K., Yokoyama, M., Yamashita, M. & Hirano, T.(2012) "Induction of excitatory and inhibitory presynaptic differentiation by GluD1" Biochem. Biophys. Res. Commun., 417, 157-161.
  71. Tanaka, H. & Hirano, T.(2012) "Visualization of subunit-specific delivery of glutamate receptors to postsynaptic membrane during hippocampal long-term potentiation" Cell Reports, 1, 291-298.
  72. Kawaguchi, S. & Hirano, T.(2013) "Gating of long-term depression by CaMKII through enhanced cGMP signaling in cerebellar Purkinje cells" J. Physiol., 591, 1707-1730.
  73. Yamashita, M., Kawaguchi, S. & Hirano, T.(2013) "Contribution of postsynaptic GluD2 to presynaptic R-type Ca2+ channel function, glutamate release and long-term potentiation at parallel fiber to Purkinje cell synapses" Cerebellum, 12, 657-666.
  74. Tanaka, S., Kawaguchi, S. Shioi, G. & Hirano, T.(2013) "Long-term potentiation of inhibitory synaptic transmission onto cerebellar Purkinje neurons contributes to adaptation of vestibulo-ocular reflex" J. Neurosci., 33, 17209-17220.
  75. Tanaka, H., Fujii, S. & Hirano, T.(2014) "Live-cell imaging of receptors around postsynaptic membrane formed on adhesion-protein-coated glass" Nature Protocols, 9, 76-89.
  76. Bando, Y., Hirano, T. & Tagawa, Y.(2014) "Dysfunction of KCNK potassium channels impairs neuronal migration in the developing mouse cerebral cortex" Cerebral Cortex, 24, 1017-1029.
  77. Nagasaki, N., Hirano, T. & Kawaguchi, S.(2014) "Opposite regulation of sustained CaMKII activity by a and b subunits impacts inhibitory synaptic plasticity" J. Physiol., 592, 4891-4909.
  78. Bando, Y., Irie, K., Shimomura, T., Umeshima, H., Kushida, Y., Kengaku, M., Fujiyoshi, Y., Hirano, T. & Tagawa, Y.(2016) "Control of spontaneous Ca2+ transients is critical for neuronal maturation in the developing neocortex" Cerebral Cortex, 26, 106-117.
  79. Nakamura, Y. & Hirano, T.(2016) "Intracellular Ca2+ thresholds for induction of excitatory long-term depression and inhibitory long-term potentiation in a cerebellar Purkinje neuron" Biochem. Biophys. Res. Commun., 469, 803-808.
  80. Fujii, S., Tanaka, H. & Hirano, T.(2017) "Detection and characterization of individual endocytosis of AMPA-type glutamate receptor around postsynaptic membrane" Genes to Cells, 22, 583-590.
  81. Wakita, R., Tanabe, S., Tabei, K., Funaki, A., Inoshita, T. & Hirano, T.(2017) "Differential regulations of vestibulo-ocular reflex and optokinetic response by b- and a2-adrenergic receptors in the cerebellar flocculus" Scientific Reports, 7, 3944, doi: 10.1038/s41598-017-04273-9.
  82. Inoshita, T. & Hirano, T.(2018) "Occurrence of long-term depression in the cerebellar flocculus during adaptation of optokinetic response" eLife, 7, e36209, doi: 10.7554/eLife.36209
  83. Funahashi, J., Tanaka, H. & Hirano, T.(2018) "Visualization of synchronous or asynchronous release of single synaptic vesicle in active-zone-like membrane formed on neuroligin-coated glass surface" Frontiers in Cellular Neuroscience, 12, 140. doi: 10.3389/fncel.2018.00140
  84. Fujii, S., Tanaka, H. & Hirano, T.(2018) "Suppression of AMPA receptor exocytosis contributes to hippocampal LTD" J. Neurosci., 38, 5523-5537. Doi: 10.1523/JNEUROSCI.3210-17.2018
  85. Merkurjev, D., Hong, W. T., Iida, K., Oomoto, I., Goldie, B. J., Yamaguti, H., Ohara, T. Kawaguchi, S. Y., Hirano, T., Martin, K. C., Pellegrini, M. & Wang, D. O.(2018) "Synaptic m6A epitranscriptome reveals functional partitioning of localized Transcripts for Dynamic Tripartite synapse modulation" Nature Neurosci., 21, 1004-1014. doi: 10.1038/s41593-018-0173-6
  86. Sumitomo A, Yukitake H, Hirai K, Horike K, Ueta K, Chung Y, Warabi E, Yanagawa T, Kitaoka S, Furuyashiki T, Narumiya S, Hirano T, Niwa M, Sibille E, Hikida T, Sakurai T, Ishizuka K, Sawa A, & Tomoda T.(2018) "Ulk2 controls cortical excitatory-inhibitory balance via autophagic regulation of p62 and GABAA receptor trafficking in pyramidal neurons" Hum. Mol. Genet., 27, 3165-3176. doi: 10.1093/hmg/ddy219.
  87. Tanaka H, Sakaguchi D, & Hirano T.(2019) "Amyloid-β oligomers suppress subunit-specific glutamate receptor increase during LTP" Alzheimer's & Dementia: Translational Research & Clinical Interventions, 5, 797-808. doi: 10.1016/j.trci.2019.10.003
  88. Inoshita T, & Hirano T.(2020) "Norepinephrine facilitates induction of long-term depression through β-adrenergic receptor at parallel fiber-to-Purkinje cell synapses in the flocculus" Neurosci., 462, 141-150, doi: 10.1016/j.neuroscience.2020.05.037.
  89.   

C 総説、コメント

  1. 平野丈夫(1987)「Caチャンネルの発生と分化」生体の科学, 38(6): 562-567.
  2. 平野丈夫(1990)「培養ニューロン間でのシナプス形成と可塑性」生体の科学, 41(3): 164-170.
  3. 平野丈夫(1990)「培養系におけるシナプス伝達の増強と抑圧」実験医学, 8(12): 28-34.
  4. 平野丈夫(1990)「小脳における長期抑圧のシナプス機構」医学のあゆみ, 155(8): 497.
  5. 平野丈夫(1991)「小脳長期抑圧の細胞機構」Brain Medical, 3(1): 49-53.
  6. 平野丈夫(1991)「小脳プルキンエ細胞における可塑性の分子生理学的解析」神経研究の進歩, 35(6): 933-940.
  7. Hirano, T.(1991) "Potentiation and depression of the synaptic transmission between cerebellar granule and Purkinje neurons in culture" Biomed. Res., 12, Suppl. 2: 115-116.
  8. Hirano,T.(1991) "Synaptic formations and modulations of synaptic transmissions between identified cerebellar neurons in culture" J.Physiol. (Paris), 85: 145-153.
  9. 平野丈夫(1993) 「培養系でのシナプス形成と可塑性」第95回日本医学会シンポジウム記録集, 小脳, 26-31.
  10. Hirano, T., Kasono, K., Shigemoto, R. and Nakanishi, S.(1994) "Induction mechanism of long term depression in cultured Purkinje neurons" Biomed. Res., 15, Suppl. 1: 79-81.
  11. 平野丈夫(1994) 「小脳培養系からみたシナプス可塑性」医学のあゆみ, 170: 590-593.
  12. 平野丈夫(1994) 「培養細胞系を用いた小脳可塑性の解析」実験医学, 12: 2461-2466.
  13. 平野丈夫(1995) 「小脳培養系におけるシナプス形成と可塑性」日本生理学雑誌, 57 増刊, 261-268.
  14. 平野丈夫(1995) 「神経組織の調製技術 小脳」実験医学別冊 脳・神経研究プロトコル, 91-95.
  15. Hirano, T.(1996) "Molecules involved in cerebellar long-term depression (LTD) and mutant mice defective in it" Behavioral and Brain Sciences, 19: 456-457.
  16. 平野丈夫(1997) 「代謝型グルタミン酸受容体」実験医学別冊, Bio Science用語ライブラリー 脳・神経, 108-109.
  17. 平野丈夫(1998) 「ノックアウトマウスを用いたグルタミン酸受容体機能の解析」神経研究の進歩 イオンチャネルとレセプター, 42: 306-316. 
  18. 平野丈夫(2000) 「長期抑圧」神経研究の進歩 小脳, 44: 723-733.
  19. Okano, H., Hirano, T. and Balaban, E.(2000) "Learning and memory" Proc. Natl. Acad. Sci. USA, 97: 12403-12404.
  20. Hirano, T., Watanabe, D., Kawaguchi, S., Pastan, I. and Nakanishi, S.(2002) "Roles of inhibitory interneurons in the cerebellar cortex" Annals of New York Academy of Science, 978: 405-412.
  21. 川口真也、平野丈夫(2003) 「GABAB受容体による小脳抑制性シナプス可塑性の制御」Gタンパク質共役受容体と脳機能 遺伝子医学, 7: 195-198.
  22. 加藤明、吉田盛史、平野丈夫(2003) 「小脳による運動制御・運動学習機構解明へ向けての分子遺伝学アプローチ」脳の科学, 6: 571-578.
  23. 平野丈夫(2004) 「小脳皮質のニューロン・回路と機能」日本神経回路学会誌, 11: 21-28.
  24. Hirano, T.(2006) "Cerebellar regulation mechanisms learned from studies on GluRd2, a unique glutamate-receptor-related molecule specifically expressed at parallel fiber-Purkinje cell synapses" Mol. Neurobiol., 33: 1-16.
  25. 矢和多智、平野丈夫(2006) 「グルタミン酸受容体の働き」実験医学, 24: 673-678.
  26. Hirano, T., Yoshida, T. and Funabiki, K.(2006) "Mechanism of cerebellar function studied using mutant mice" The Cerebellum, 5: 299-300.
  27. 平野丈夫(2008) 「小脳シナプスの可塑性と運動学習」蛋白質 核酸 酵素, 53: 549-554.
  28. Tagawa, Y., Mizuno, H. and Hirano T.(2008) "Activity-dependent development of interhemispheric connections in the visual cortex" Reviews in the Neurosciences, 19: 19-28.
  29. 平野丈夫(2009) 「小脳シナプス可塑性の制御機構とはたらき」神経科学ニュース, 174: 34-36.
  30. Hirano, T.(2009) "Regulation mechanism and roles of cerebellar synaptic plasticity" 神経科学ニュース, 174: 32-34.
  31. 川口真也、平野丈夫(2010) 「CaMK IIによるシナプスの構造と機能調節」生体の科学, 61(5), 458-459.
  32. 川口真也、平野丈夫(2010) 「Calcineurinによるシナプスの多彩な制御」生体の科学, 61(5), 466-467.
  33. 平野丈夫(2011)「前庭動眼反射と視運動性眼球運動の適応への小脳シナプス可塑性の関与」Equilibrium Research, 70(2), 104-109.
  34. 山下愛美、平野丈夫(2011) 「小脳での可塑性」Clinical Neuroscience, 29: 791-793.
  35. Hirano, T.(2012) "Glutamate-receptor-like molecule GluRd2 involved in synapse formation at parallel fiber-Purkinje neuron synapses" The Cerebellum, 11: 71-77.
  36. Hirano, T. & Kawaguchi, S.(2012) "Regulation of inhibitory synaptic plasticity in a Purkinje neuron" The Cerebellum, 11: 453-454.
  37. 田中進介、平野丈夫(2012) 「小脳学習における抑制性ニューロン」Clinical Neuroscience, 30: 1375-1376.
  38. Tagawa, Y. & Hirano, T.(2012) "Activity-dependent callosal axon projections in neonatal mouse cerebral cortex", Neural Plasticity, ID 797295, doi:10.1155/2012/797295, 1-10.
  39. Hirano, T.(2013) "Long-term depression and other synaptic plasticity in the cerebellum" Proceedings of the Japan Academy, Series B, 89: 183-195.
  40. Hirano, T. & Kawaguchi, S.(2014) "Regulation and functional roles of rebound potentiation at cerebellar stellate cell - Purkinje cell synapse" Frontiers in Cellular Neuroscience, 8, 42: 1-8. doi: 10.3389/fncel.2014.00042
  41. Hirano, T.(2014) "Around LTD hypothesis in motor learning" Cerebellum, 12: 645-650. doi: 10.1007/s12311-014-0581-4
  42. Hirano, T., Yamazki, Y. & Nakamura, Y.(2016) "LTD, RP and motor learning" Cerebellum, 15: 51-53. doi: 10.1007/s12311-015-0698-0
  43. 平野丈夫(2016) 「異シナプス可塑性とLTD」Clinical Neuroscience, 34: 874-875.
  44. 平野丈夫(2017) 「Q & A - 神経科学の素朴な疑問、小脳皮質はどこでも同じ構造なのですか?」Clinical Neuroscience, 35: 897.
  45. Hirano, T.(2018) "Regulation and interaction of multiple types of synaptic plasticity in a Purkinje neuron and their contribution to motor learning" Cerebellum, 17: 756-765, doi: 10.1007/s12311-018-0963-0
  46. Hirano, T.(2018) "Purkinje Neurons: Development, Morphology and Function" Cerebellum, 17: 699-700, doi: 10.1007/s12311-018-0985-7
  47. Hirano, T.(2018) "Visualization of exo- and endocytosis of AMPA receptors during hippocampal synaptic plasticity around postsynaptic-like membrane formed on glass surface" Frontiers in Cellular Neuroscience, 12: 442, doi: 10.3389/fncel.2018.00442
  48. 井下拓真、平野丈夫(2019) 「LTDとrebound potentiationのOKR制御における役割」Clinical Neuroscience, 37: 940-942.
  49.